Diffusion and segmental dynamics of double-stranded DNA.

نویسندگان

  • E P Petrov
  • T Ohrt
  • R G Winkler
  • P Schwille
چکیده

Diffusion and segmental dynamics of the double-stranded lambda-phage DNA polymer are quantitatively studied over the transition range from stiff to semiflexible chains. Spectroscopy of fluorescence fluctuations of single-end fluorescently labeled monodisperse DNA fragments unambiguously shows that double-stranded DNA in the length range of 10(2) - 2 x 10(4) base pairs behaves as a semiflexible polymer with segmental dynamics controlled by hydrodynamic interactions.

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عنوان ژورنال:
  • Physical review letters

دوره 97 25  شماره 

صفحات  -

تاریخ انتشار 2006